Lagavulin
Lagavulin is an Act 1 elite enemy with 109-111 HP and is widely considered the hardest elite in the game. For the first 3 turns (or until hit 3 times), it sleeps with 8 Metallicize, blocking 8 damage per turn. Once awakened, it alternates between Siphon Soul (drains 1 Strength and 1 Dexterity from the player) and Attack (18-21 damage), with the Siphon Soul drain continuing every other turn.
Lagavulin demands either very high early burst damage (to kill it during its sleeping phase) or a deck capable of sustaining through its stat drains. Characters that do not rely heavily on Strength or Dexterity (like Defect Orb builds) are less impacted by Siphon Soul. It is one of the few enemies where skipping the elite fight is often correct if your deck is not ready. The relic Juzu Bracelet makes Lagavulin significantly easier by preventing the Siphon Soul debuffs.