Nemesis

Nemesis is an Act 3 elite enemy with 185/200 HP. It has Intangible on alternating turns (reducing all damage it takes to 1), and on its attacking turns it uses Scythe (18 damage), Attack (6 damage x3), and Shuffle (adds 3 Burn cards to the player's draw pile). It strictly alternates between Intangible turns and attack turns.

Nemesis's alternating Intangible means you can only deal meaningful damage on every other turn. Using Block and setup cards on Intangible turns and front-loading all damage on attack turns is the fundamental pattern. The Burn cards it adds deal 2 damage when drawn or held at end of turn, accumulating over the fight. Efficient single-target burst on non-Intangible turns, combined with strong Block on Intangible turns, is the winning strategy.