Slime Boss
The Slime Boss is one of three Act 1 boss enemies with 140/150 HP (normal/ascension). It rotates through Goop Spray (adds 5 Slimed cards to discard, deals 0 damage), Preparing (does nothing), and Slam (35-38 damage). When it reaches 50% HP, it Splits into one Large Acid Slime and one Large Spike Slime, each inheriting the current HP.
The key challenge of the Slime Boss fight is managing the Split. If your deck relies heavily on cycling, the growing number of Slimed cards becomes a major problem. Ideally, you want to burst the Slime Boss from above 50% to below in a single large turn to kill it outright, avoiding the Split entirely. Having strong single-target burst, high Block to survive Slam, and ways to handle Slimed card pollution (like small decks or Exhaust effects) makes this fight manageable.