Spike Slime L

The Large Spike Slime is a substantial Act 1 enemy with 64-72 HP. It repeatedly uses Flame Tackle (16-22 damage, adds 1 Slimed to discard) and at 50% HP Splits into two Medium Spike Slimes. Its consistent high-damage Flame Tackle attacks make it one of the more threatening normal enemies in Act 1.

The Large Spike Slime's Flame Tackle can quickly wear down HP if you do not have adequate Block. Killing it efficiently (under 50% HP in one shot) avoids dealing with two Medium Spike Slimes. Multi-hit attacks and burst damage are valuable here. Decks focused on Block should have a reliable way to handle its consistent damage output before their HP erodes.