Red Mask
Red Mask is an event relic that can be obtained from a specific random event. At the start of each combat, all enemies start with 1 stack of Weak. Weak causes enemies to deal 25% less damage per attack. It can only be obtained through the Masked Bandits event.
Red Mask provides consistent passive damage reduction across every combat in the run. Starting each fight with Weak on all enemies reduces the threat of early attacks while you set up your turns, and in Elite and Boss encounters where damage is most dangerous, entering with enemies already Weakened is a significant safety advantage. The relic has no downside and is essentially free damage mitigation for every fight. It is particularly valuable in Act 2 and Act 3 where enemies deal large amounts of damage and Weak's 25% reduction becomes increasingly meaningful. It synergizes with other defensive tools and with builds that need time to set up before exerting full offensive pressure.