Poison

Poison is a stacking debuff that causes the affected target to lose HP equal to its current stack count at the start of their turn, then reduces the stack count by 1. Unlike direct damage, Poison damage bypasses Block. The stacks do not reset between turns — they persist and decay gradually, meaning high Poison stacks deal substantial damage over multiple turns.

Poison is the signature mechanic of The Silent, with cards like Deadly Poison, Noxious Fumes, Envenom, and Bouncing Flask. A Poison-focused Silent build typically stacks large amounts of Poison on a boss over the first few turns and then focuses on defending while the Poison kills the enemy. Corpse Explosion is especially powerful, dealing massive area damage when a Poisoned enemy dies. The Snecko Eye and Poison Potion can provide Poison outside of The Silent's kit.